Hervé Seligmann

CURRICULUM VITAE

Hervé Seligmann

Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes

Faculté de Médecine, URMITE CNRS-IRD 198 UMR 6236

Université Aix-Marseille, 13385 Marseille, France

Email: podarcissicula@gmail.com

Nationality: Luxemburg-Israeli

Born 08 III 1966, Grand Duchy of Luxemburg

Education:

1985-88  B. Sc. in Biology, at The Hebrew University of Jerusalem.

  • Sc. in Plant Physiology; thesis, « A morphological marker of transitions towards salt adaptation in Sorghum bicolor« , supervision of Dr RH Lerner, Dept of Plant Sciences, The Hebrew University of Jerusalem.
  • D. in lizard microevolution, “Microevolution of proneness to tail loss in lizards” Prof Yehudah L. Werner, Dept of ESE, The Hebrew University of Jerusalem and Dr Avigdor Beiles, Institute for Evolution, University of Haifa.

Main research interests:

(a) Emergence of adaptive information and evolution.

(b) Community ecology and stability.

(c) Morphogenesis

Appointments at the Hebrew University:

2000-01 Teaching assistant in first year courses “An introduction to ecology and population biology”;

“Basic laboratory for Ecology”; and second year course “An introduction to marine invertebrates”.

1999-00 Teaching assistant in third year course “Ecology of nature conservation”.

1998-99 Teaching assistant in third year course “An introduction to amphibians and reptiles of Israel”.

1997-99 Teaching assistant in first year course “An introduction to ecology and population biology”.

Other appointments:

2021      Invited researcher, International Excellence Fellowship of Karlsruhe Institute of Technology (KIT)

2015-18 Invited professor, A*MIDEX excellence project at URMITE.

2013-15 Invited professor, URMITE CNRS-IRD 198 UMR 6236,Faculté de Médecine, Aix-Marseille

University, project: alternative coding in bacteria and giant viruses.

2007-08 Half time field and laboratory technician of Yaron Ziv, Spatial Ecology laboratory, Dept.

of Life Sciences, Ben Gurion University of the Negev.

2004-5 External lecturer in 3 courses: “Principles of Biology A: cell biology”, “Principles of Biology B: from organisms to ecosystems” and “Cell Physiology”, the Jerusalem College of Technology.

Postdoctoral training:

2020       IDEX project on origins of life, through biochemical and informatic approaches, AGEIS EA 7407 + Labcom (CNRS/UGA/Orange® Telecoms4Health)

2010- 13 Projects on overlapping genetic codes in vertebrate mitochondria at the Natural History Museum collections of the Hebrew University of Jerusalem.

2008-10 Project in theoretical biology with Thomas F Hansen, Center for Ecological & Evolutionary Synthesis, University of Oslo.

2002-04 Project on molecular evolution of vertebrate mitochondrial genomes with Dr David

Pollock, Department of Biological Sciences, Louisiana State University.

2001-02 Project on molecular mechanisms of developmental instability, sponsored by

Professor Leigh VanValen at the Department of Ecology & Evolution, University of Chicago.

2000-01 Project on New Zealand’s herpetofauna, with Charles D Daugherty, Victoria Univ. at Wellington

Awards: Rothschild fellowship (27000 US $ +10500 $ family help) for the year 2001-2.

A*MIDEX fellowship (450000 euros) for 2015-18

Languages: French, German, Luxemburgish, Hebrew, English. (Latin).

Other interests: Conservation of nature, nature photography, culture and language structures, history.

Sports: Hiking, semi-long distance running, archery.

Reviewed for: African J Biotech 2011-4; American Naturalist 2013; Animal Behavior 2003; Annals NY Acad Sci 2018; Biochemical Society Transactions 2016; BBA Proteins & Proteomics 2019; Bioessays 2011-20; Bioinformatics 2020; Biology Direct 2020; Biosystems 2006-20; BMC Evol Biol 2007-19; BMC Genomics 2009-15; BMC Research Notes 2009; Cancer Therapy 2014; Cell MDPI 2020; Cell Mol Life Sci 2017; Chirality 2015; Comput Biol Chem 2014-5; Comput Struct Biotechnol J 2020; Curr Bioinformatics 2018-20; Curr Chem Biol 2015; Curr Zool 2011; Diversity & Distributions 2005; Evolutionary Bioinformatics 2007; Front Genetics 2020; Front Public Health 2020;  Front Oncology 2020; Front Microbiol 2020; Gene 2020; Genes 2019; Genome 2019; Gene Reports 2020; Heredity 2005; Int J Biol Macromol 2019-2020; Int J Mol Sci 2017-9; iScience 2020; Israel J Ecol Evol 2006-17; J Biol Eng 2008; J Clinical Laboratory Analysis 2019; J Endocrinology 2019; J Evol Biol 2019; J Evol Biol Res 2011; J Genetics & Genomics Res 2014-6; J Herpetol 2007;J Mol Biol 2018; J Mol Evol 2007-20; J Morphol 2011-4; J Theor Biol 2005-20; Life 2011-20; Medical Hypotheses 2015; Microbial Informatics 2012; Microbiology 2003; Mitochondrial DNA 2014; Mitochondrion 2008; Mol Biol Evol 2020; Mol Microbiol 2005; Mol Phyl Evol 2021; Naturwissenschaften 2019; North Western J Zool 2011; Nuc Acids Res 2007-19; Phosphorus, Sulfur, and Silicon and the Related Elements 2017; PLoS Comput Biol 2016-18; PLoS One 2013; Prog Biophys Mol Biol 2019-20; RNA Biol 2019; Science of the Total Environment 2020; Scientifica 2020; Scientific Reports 2016; Symmetry 2018-9; The J Franklin Institute 2015; Total Environmental Science 2020; Toxicology 2012; Turkish J Zool 2013; Virologica Sinica 2019; Virus Res 2018; Viruses 2019; World J Biol Chem 2010-1; Yeast 2018.

Edited books:

Seligmann H 2011 DNA Replication-Current Advances. InTech publisher, pp. 694.

Seligmann H, Warthi G 2018 M. Mitochondrial DNA- New insights. InTech publisher, pp. 150.

Publications, peer reviewed

  1. Demongeot J, Seligmann H 2022 Evolution of small and large ribosomal RNAs from accretion of tRNA subelements. Biosystems 222, 104796.
  2. Demongeot J, Oshinubi K, Rachdi M, Seligmann H, Thuderoz F, Waku J 2021 Estimation of daily reproduction numbers in Covid-19 outbreak. Computation MDPI (Basel) 9, 109.
  3. Seligmann H Vuillerme N, Demongeot J 2021 Unpredictable, counter-intuitive geoclimatic and demographic correlations of Covid-19 spread rates. Biology MDPI (Basel) 10, 623.
  4. Seligmann H 2021 Balanced evaluation of preliminary data on a candidate COVID-19 hydroxychloroquine treatment. International Journal of Antimicrobial Agents 57, 106292.
  5. Nesterov-Mueller A, Popov R, Seligmann H 2020 Combinatorial fusion rules to describe codon assignment in the standard genetic code. Life (Basel) 11, e4
  6. Demongeot J, Moreira A, Seligmann H 2021 Negative CG dinucleotide bias: An explanation based on feedback loops between Arginine codon assignments and theoretical minimal RNA rings. Bioessays, e2000071.
  7. Demongeot J, Seligmann H 2021 Codon assignment evolvability in theoretical minimal RNA rings. Gene 769, 145208.
  8. Demongeot J, Seligmann H 2020 SARS-CoV-2 and miRNA-like inhibition power. Medical Hyp 144, 110245.
  9. Seligmann H, Iggui S, Rachdi M, Vuillerme N, Demongeot J 2020 Inverted covariate effects for mutated 2nd vs 1st wave Covid-19: high temperature spread biased for young. Biology (Basel) 9, 226.
  10. Seligmann H, Warthi G 2020 Natural pyrrolysine-biased translation of stop codons in mitochondrial peptides entirely coded by expanded codons. Biosystems, in press.
  11. Demongeot J, Flet-Berliac Y, Seligmann H 2020 Temperature decreases spread parameters of the new covid-19 cases dynamics. Biology (Basel) 9, 10.
  12. Seligmann H 2020 First arrived, first served: competition between codons for codon-amino acid stereochemical interactions determined early genetic code assignments. Naturwissenschaften 107, 20.
  13. Demongeot J, Seligmann H 2020 Comparisons between small ribosomal RNA and theoretical minimal RNA ring secondary structures confirm phylogenetic and structural accretion histories. Scientific Reports 10, 7693.
  14. Demongeot J, Seligmann H 2020 Why is AUG the start codon? Bioessays, e1900201.
  15. Demongeot J, Seligmann H 2020 Deamination gradients within codons after 1<->2 position swap predict amino acid hydrophobicity and parallel β-sheet conformational preference. Biosystems 191-192, 104116.
  16. Demongeot J, Seligmann H 2020 Theoretical minimal RNA rings mimic molecular evolution before tRNA-mediated translation: codon-amino acid affinities increase from early to late RNA rings. C R Biol 343, 111-122.
  17. Demongeot J, Seligmann H 2020 Accretion history of large ribosomal subunits deduced from theoretical minimal RNA rings is congruent with histories derived from phylogenetic and structural methods. Gene 738, 144436.
  18. Warthi G, Fournier PE, Seligmann H 2020 Origins of 347 unknown ESTs indicates putative transcription of non-coding genomic regions. Front Genetics 11, 42.
  19. Demongeot J, Seligmann H 2020 The primordial tRNA acceptor stem code from theoretical minimal RNA ring clusters. BMC Genetics 21, 7.
  20. Demongeot J, Seligmann H 2020 RNA rings strengthen hairpin accretion hypotheses for tRNA evolution: a reply to commentaries by Z.F. Burton and M. Di Giulio. J Mol Evol 88, 243-252.
  21. Seligmann H, Demongeot J 2020 Codon directional asymmetry suggests swapped prebiotic 1st and 2nd codon positions. Int J Mol Sci 21, 347.
  22. Demongeot J, Seligmann H 2020 Pentamers with non-redundant frames: bias for natural circular code codons. J Mol Evol 88, 194-201.
  23. Warthi G, Fournier PE, Seligmann H 2020 Identification of noncanonical transcripts produced by systematic nucleotide exchanges in HIV-associated centroblastic lymphoma. DNA Cell Biol 39, 1444-1448.
  24. Seligmann H, Warthi G 2019 Chimeric translation for mitochondrial peptides: regular and expanded codons. Comput & Struct Biotech J 17, 1195-1202.
  25. Seligmann H 2019 Syntenies between cohosted mitochondrial, chloroplast and Phycodnavirus genomes: functional mimicry and/or common ancestry? DNA Cell Biol 38, 786-795.
  26. Demongeot J, Seligmann H 2019 The Uroboros theory of life’s origin: 22-nucleotide theoretical minimal RNA rings reflect evolution of genetic code and tRNA-rRNA translation machineries. Acta Biotheoretica, 67: 273-297.
  27. Demongeot J, Seligmann H 2019 Evolution of tRNA into rRNA secondary structures. Gene Rep, in press.
  28. Demongeot J, Seligmann H 2019 Theoretical minimal RNA rings designed according to coding constraints mimick deamination gradients. Naturwissenschaften 106, 44.
  29. Warthi G, Seligmann H 2019 Transcripts with systematic nucleotide deletion of 1-12 nucleotide in human mitochondrion suggest potential non-canonical transcription. PLoS One 14, e0217356.
  30. Seligmann H 2019 Localized context-dependent effects of the « ambush » hypothesis: more mitogenomic off frame stop codons downstream of shifty codons. DNA Cell Biol 38, 786-795.
  31. Demongeot J, Seligmann H 2019 Bias for 3′-dominant codon directional asymmetry in theoretical minimal RNA rings. J Comput Biol 26, 1003-1012.
  32. Demongeot J, Seligmann H 2019 Spontaneous evolution of circular codes in theoretical minimal RNA rings. Gene, 705, 95-102.
  33. Demongeot J, Seligmann H 2019 Theoretical minimal RNA rings recapitulate the order of the genetic code’s codon-amino acid assignments. J Theor Biol 471, 108-116.
  34. Demongeot J,Seligmann H 2019 More pieces of ancient than recent theoretical minimal proto-tRNA-like RNA rings in genes coding for tRNA synthetases. J Mol Evol 87, 152-174.
  35. Seligmann H 2019 Giant viruses: spore-like intermediates between Rickettsia and mitochondria? Ann NY Acad Sci 1443, 69-79.
  36. Warthi G, Seligmann H 2018 Swinger RNAs in the human mitochondrial transcriptome. Chapter in: Mitochondrial DNA, Seligmann H and Warthi G eds, InTechOpen,
  37. Seligmann H 2018 Directed mutations recode mitochondrial genes: from regular to stopless genetic codes. Chapter in: Mitochondrial DNA, Seligmann H and Warthi G eds, InTechOpen,
  38. Seligmann H 2018 Giant viruses as protein-coated amoeban mitochondria? Virus Res 253, 77-86.
  39. El Houmami N, Durand G, Bzdrenga J, Darmon A, Minodier P, Seligmann H, Raoult D, Fournier P-E 2018 A new highly sensitive and specific real-time PCR assay targeting the malate dehydrogenase gene of Kingella kingae and application to 201 pediatric clinical specimens. J Clin Microbiol 56, e00505-18.
  40. Seligmann H 2018 Protein sequences recapitulate genetic code evolution. Comput & Struct Biotech J 16, 177-189.
  41. Seligmann H 2018 Alignment-based and alignment-free methods converge with experimental data on amino acids coded by stop codons at split between nuclear and mitochondrial genetic codes. Biosystems 167, 33-46.
  42. Faiman R, Abergil D, Babocsay G, Razzetti E, Seligmann H, Werner YL 2018 A review of sexual dimorphism of eye size in Colubroidea snakes. Vertebrate Zoology 68, 91-108.
  43. Bekliz M, Azza S, Seligmann H, Decloquement P, Raoult D, La Scola B 2018 Experimental analysis of mimivirus translation initiation factor 4a reveals its importance for viral proteins translation during infection of Acanthamoeba polyphaga. J Virology 92, e00337-18.
  44. Abrahão J, Silva L, Silva L, Bou Khalil J, Rodrigues R, Arantes T, Assis F, Boratto P, Andrade M, Kroon E, Ribeiro B, Bergier I, Seligmann H, Ghigo E, Colson P, Levasseur A, Kroemer G, Raoult D, La Scola B. 2018. Tailed giant Tupanvirus possesses the most complete translational apparatus of the virosphere. Nature Communications 9, 749.
  45. Seligmann H, Raoult D. 2018. Stem-loop RNA hairpins in giant viruses: invading rRNA-like repeats and a template free RNA. Frontiers in Microbiology -Virology 9, 101.
  46. Seligmann H. 2018. Bijective codon transformations show genetic code symmetries centered on cytosine’s coding properties. Theory in Biosciences 137, 17-31.
  47. Seligmann H, Warthi G. 2017. Genetic code optimization for cotranslational protein folding: codon directional asymmetry correlates with antiparallel betasheets, tRNA synthetase classes. Comput & Struct Biotech J 15, 412-424.
  48. Seligmann H. 2017. Reviewing evidence for systematic transcriptional deletions, nucleotide exchanges, and expanded codons, and peptide clusters in human mitochondria. Biosystems 160, 10-24.
  49. El Houmami N, Bzdrenga J, Durand G, Minodier P, Seligmann H, Prudent E, Bakour S, Bonacorsi S, Raoult D, Yagupsky P, Fournier PE. 2017. Molecular tests that target the RTX locus do not distinguish between Kingella kingae and the recently described Kingella negevensis Journal of Clinical Microbiology 55, 3113-3122.
  50. El Houmami N, Bakour S, Bzdrenga J, Rathored J, Seligmann H, Robert C, Armstrong N, Schrenzel J, Raoult D, Yagupsky P, Fournier PE. 2017. Isolation and characterization of Kingella negevensis Nov., a novel Kingella species detected in a healthy paediatric population. International Journal of Systematic and Evolutionary Microbiology 67, 2370-2376.
  51. El Houmami N, Seligmann H. 2017. Evolution of nucleotide punctuation marks: from structural to linear signals. Frontiers in Genetics, section Bioinformatics and Computational Biology 8, 36.
  52. El Houmami N, Minodier P, Bouvier C, Seligmann H, Raoult D, Fournier P-E. 2017. Primary subacute epiphyseal osteomyelitis caused by Mycobacterium species in young children: a modern diagnostic approach. European Journal of Clinical Microbiology &Infectious Diseases 36, 771-7.
  53. Osei L, El Houmami N, Minodier P, Sika A, Basset T, Seligmann H, Terraz A, Demar M, Pochard J, Clouzeau J, Fournier P-E, ElengaN. Pediatric bone and joint infections in French Guiana: a 6-year retrospective review. Journal of Tropical Pediatrics 63, 380-388.
  54. Seligmann H. 2017. Natural mitochondrial proteolysis confirms transcription systematically exchanging/deleting nucleotides, peptides coded by expanded codons. Journal of Theoretical Biology, 414, 76-90.
  55. Seligmann H. 2016. Unbiased mitoproteome analyses confirm non-canonical RNA, expanded codon translations. Comput & Struct Biotech J 14, 391-403.
  56. Seligmann H. 2016. Natural chymotrypsin-like-cleaved human mitochondrial peptides confirm tetra-, pentacodon, non-canonical RNA translations. Biosystems 147, 78-93.
  57. Seligmann H. 2016. Chimeric mitochondrial peptides from contiguous regular and swinger RNA. Comput & Struct Biotech J 14, 283-97.
  58. Barthélémy R-M, Seligmann H. 2016. Cryptic tRNAs in chaetognath mitochondrial genomes. Computational Biology and Chemistry 62, 119-32.
  59. Seligmann H. 2016. Swinger RNA self-hybridization and mitochondrial non-canonical swinger transcription, transcription systematically exchanging nucleotides. Journal of Theoretical Biology 399, 84-91.
  60. Seligmann H. 2016. Systematically frameshifting by deletion of every 4th or 4th and 5th nucleotides during mitochondrial transcription: RNA self-hybridization regulates delRNA expression. Biosystems 142, 43-51.
  61. Seligmann H. 2016. Translation of mitochondrial swinger RNAs according to tri-, tetra- and pentacodons. Biosystems 140, 38-48.
  62. Seligmann H, Raoult D.2016. Unifying view of stem-loop hairpin RNA as origin of current and ancient parasitic and non-parasitic RNAs, including in giant viruses. Current Opinion in Microbiology 31, 1-8.
  63. Seligmann H. 2015. Codon expansion and systematic transcriptional deletions produce tetra-, pentacoded mitochondrial peptides. Journal of Theoretical Biology 387, 154-65.
  64. Seligmann H. 2015. Systematic exchanges between nucleotides: Genomic swinger repeats and swinger transcription in human mitochondria. Journal of Theoretical Biology 384, 70-7.
  65. Seligmann H. 2015. Swinger RNAs with sharp switches between regular transcription and transcription systematically exchanging ribonucleotides: case studies. Biosystems 135, 1-8.
  66. Seligmann H. 2016. Sharp switches between regular and swinger mitochondrial replication: 16S rDNA systematically exchanging nucleotides A<->T+C<->G in the mitogenome of Kamimuria wangi. Mitochondrial DNA A DNA MappSeq Anal 27, 2440-6.

59.Seligmann H. 2015. Phylogeny of genetic codes and punctuation codes within genetic codes. Biosystems 129, 36-43.

  1. Seligmann H. 2014. Mitochondrial swinger replication: DNA replication systematically exchanging nucleotides and short 16S ribosomal DNA swinger inserts. Biosystems 125, 22-31.
  2. Seligmann H. 2014.Species radiation by DNA replication that systematically exchanges nucleotides? Journal of Theoretical Biology 363, 216-22.
  3. Seligmann H., Labra A. 2014. The relation between hairpin formation by mitochondrial WANCY tRNAs and the occurrence of the light strand replication origin in Lepidosauria. Gene 542, 248-57.
  4. Michel C.A, Seligmann H. 2014. Bijective transformation circular codes and nucleotide exchanging RNA transcription. BioSystems 118, 39-50.
  5. Seligmann H. 2014. Putative anticodons in mitochondrial tRNA sidearm loops: pocketknife tRNAs? Journal of Theoretical Biology 340, 155-63.
  6. Seligmann H., Labra A. 2013. Tetracoding increases with body temperature in Lepidosauria. Biosystems 114, 155-63.
  7. Seligmann H. 2013. Pocketknife tRNA hypothesis: anticodons in mammal mitochondrial tRNA side-arm loops translate proteins? BioSystems 113, 165-76.
  8. Seligmann H. 2013. Triplex DNA:RNA, 3’-to-5’ inverted RNA and protein coding in mitochondrial genomes. Journal of Computational Biology 20, 1-12.
  9. Seligmann H. 2013. Polymerization of non-complementary RNA: systematic symmetric nucleotide exchanges mainly involving uracil produce mitochondrial RNA transcripts coding for cryptic overlapping genes. Biosystems 111, 156-74.
  10. Seligmann H. 2013. Systematic asymmetric nucleotide exchanges produce human mitochondrial RNAs cryptically encoding for overlapping protein coding genes. Journal of Theoretical Biology 324, 1-20.
  11. Seligmann H. 2013. Replicational mutation gradients, dipole moments, nearest neighbor effects and DNA polymerase gamma fidelity in human mitochondrial genomes. The Mechanisms of DNA Replication, Stuart D. (ed.), InTech, chapter 10, 257-86.
  12. Seligmann H. 2013. Putative protein-encoding genes within mitochondrial rDNA and the D-Loop region. Ribosomes: molecular structure, role in biological functions and implications for genetic diseases, chapter 4, Lin Z and Liu W (eds), pp 67-86.
  13. Seligmann H. 2012. Putative mitochondrial polypeptides coded by expanded quadruplet codons, decoded by antisense tRNAs with unusual anticodons. Biosystems 110, 84-106.
  14. Seligmann H. 2012. Overlapping genetic codes for overlapping frameshifted genes in Testudines, and Lepidochelys olivacea as a special case. Computational Biology and Chemistry 41, 18-34.
  15. Seligmann H. 2012. Overlapping genes coded in the 3′-to-5′-direction in mitochondrial genes and 3′-to-5′ polymerization of non-complementary RNA by an ‘invertase’. Journal of Theoretical Biology, 318, 38-52.
  16. Seligmann H. 2012. Positive and negative cognate amino acid bias affects compositions of aminoacyl-tRNA synthetases and reflects functional constraints on protein structure. BIO 2, 11-26.
  17. Seligmann H. 2012. An overlapping genetic code for frameshifted overlapping genes in Drosophila mitochondria: Antisense antitermination tRNAs UAR insert serine. Journal of Theoretical Biology 298, 51-76.
  18. Seligmann H. 2012. Coding constraints modulate chemically spontaneous mutational replication gradients in mitochondrial genomes. Current Genomics 13, 37-54, invited review.
  19. Faure E., Delaye L., Tribolo S., Levasseur A., Seligmann H., Barthélémy R.-M. 2011. Probable presence of an ubiquitous cryptic mitochondrial gene on the antisense strand of the cytochrome oxidase I gene. Biology Direct 6, 56.
  20. Seligmann H. 2011.Two genetic codes, one genome: Frameshifted primate mitochondrial genes code for additional proteins in presence of antisense antitermination tRNAs. Biosystems 105, 271-85.
  21. Seligmann H. 2011.Mutation patterns due to converging mitochondrial replication and transcription increase lifespan, and cause growth rate-longevity tradeoffs. DNA Replication-Current Advances, Seligmann H. (ed.), InTech, book chapter 6, 151-80.
  22. Seligmann H. 2011.Error compensation of tRNA misacylation by codon-anticodon mismatch prevents translational amino acid misinsertion. Computational Biology and Chemistry 35: 81-95.
  23. Seligmann H. 2011. Left-handed Sphenodons grow more slowly. Advances in Medicine and Biology 24, chapter 4, 185-206, Berhardt LV (ed).
  24. Seligmann H. 2011. Pathogenic mutations in antisense mitochondrial tRNAs. Journal of Theoretical Biology 269, 287-96.
  25. Labra A., Voje K.L., Seligmann H., Hansen T.F. 2011. Evolution of the third eye: A phylogenetic comparative study of parietal-eye size as an ecophysiological adaptation in Liolaemus lizards. Biological Journal of the Linnean Society 102, 237-38 (correction).
  26. Labra A., Voje K.L., Seligmann H., Hansen T.F. 2010. Evolution of the third eye: A phylogenetic comparative study of parietal-eye size as an ecophysiological adaptation in Liolaemus lizards. Biological Journal of the Linnean Society 101, 870-83.
  27. Seligmann H. 2010. Undetected antisense tRNAs in mitochondria? Biology Direct 5, 39.
  28. Seligmann H. 2010. Avoidance of antisense antiterminator tRNA anticodons in vertebrate mitochondria. Biosystems 101, 42-50.
  29. Seligmann H. 2010. Do anticodons of mysacylated tRNAs preferentially mismatch codons coding for the misloaded amino acid? BMC Molecular Biology 11, 41.
  30. Seligmann H. 2010. The ambush hypothesis at the whole organism level: Off frame, ‘hidden’ stops in vertebrate mitochondrial genes increase developmental stability. Computational Biology and Chemistry 34, 80-5.
  31. Seligmann H. 2010.Positive correlations between molecular and morphological rates of evolution. Journal of Theoretical Biology 264, 799-807.
  32. Seligmann H. 2010. Mitochondrial tRNAs as light strand replication origins: similarity between anticodon loops and the loop of the light strand replication origin predicts initiation of DNA replication. Biosystems 99, 85-93.
  33. Babocsay G., Talbi R., Shacham B., Seligmann H. 2009. Nocturnal or diurnal? Notes on the daily activity pattern and life history of the Middle Eastern Elegant Racer Platyceps elegantissimus (Günther, 1878) (Squamata: Serpentes: Colubridae). Herpetozoa 22, 173-80.
  34. Seligmann H.2008. Hybridization between mitochondrial heavy strand tDNA and expressed light strand tRNA modulates the function of heavy strand tDNA as light strand replication origin. Journal of Molecular Biology379, 188-99.
  35. Seligmann H., Moravec J., Werner Y.L. 2008. Morphological, functional and evolutionary aspects of tail autotomy and regeneration in the “living fossil” Sphenodon (Reptilia: Rhynchocephalia). Biological Journal of the Linnean Society 93, 721-43.
  36. Krishnan N.M., Seligmann H., Rao B.J. 2008. Relationship between mRNA secondary structure and sequence variability in chloroplast genes: possible life history implications. BMC Genomics 9, 48.
  37. Seligmann H. 2007. Cost minimization of ribosomal frameshifts. Journal of Theoretical Biology 249, 162-7.
  38. Seligmann H., Anderson, S.C., Kellar, A., Bouskila, A., Saf, R., Tuniyev, B.S., Werner, Y.L. 2007. Analysis of the locomotor activity of a nocturnal desert lizard (Reptilia: Gekkonidae: Teratoscincus scincus) under varying moonlight. Zoology 110, 104-17.
  39. Seligmann H., Krishnan, N.M., Rao, B.J. 2006. Mitochondrial tRNA sequences as unusual replication origins: pathogenic implications for Homo sapiens. Journal of Theoretical Biology 243, 375-85.
  40. Seligmann H. 2006. Error propagation across levels of organization: from chemical stability of ribosomal RNA to developmental stability. Journal of Theoretical Biology242, 69-80.
  41. Seligmann H., Krishnan, N.M. 2006. Mitochondrial replication origin stability and propensity of adjacent tRNA genes to form putative replication origins increase developmental stability in lizards. Journal of Experimental Zoology B 306B, 433-49.
  42. Seligmann H., Krishnan, N.M., Rao, B.J. 2006. Possible multiple origins of replication in primate mitochondria: alternative role of tRNA sequences. Journal of Theoretical Biology 241, 321-32.
  43. Raina, S.Z., Faith, J.J., Disotell, T.R., Seligmann, H., Stewart, C.B, Pollock, D.D. 2005. Evolution of base frequency gradients in primate mitochondrial genomes. Genome Research15, 665-73.
  44. Krishnan, N.M., Seligmann, H., Raina, S.Z., Pollock, D.D. 2004. Detecting gradients of asymmetry in site-specific substitutions in mitochondrial genomes. DNA and Cell Biology 23, 707-14.
  45. Seligmann, H., Pollock, D.D. 2004. The ambush hypothesis: hidden stops prevent off-frame gene reading. DNA and Cell Biology 23, 701-5.
  46. Krishnan, N.M., Seligmann, H., de Kooning, A.P.J., Stewart, C.B., Pollock, D.D. 2004. Ancestral sequence reconstruction in primate mitochondrial DNA: Compositional bias and effect on functional inference. Molecular Biology and Evolution 21, 1871-83.
  47. Seligmann, H. 2003. More transparency in reviewing is called for. British Medical Journal 25, 989-990. Invited letter.
  48. Seligmann, H. 2003. Cost minimization of amino acid usage. Journal of Molecular Evolution 56, 151-61.
  49. Seligmann, H., Beiles, A., Werner, Y.L. 2003. More injuries in left-footed lizards. Journal of ZoologyLondon260, 129-44.
  50. Seligmann, H., Beiles, A., Werner, Y.L. 2003. Avoiding injury or adapting to survive injury? Two coexisting strategies in lizards. Biological Journal of the Linnean Society 78, 307-24.
  51. Seligmann, H., Amzallag, G.N. 2002. Chemical interactions between amino acid and RNA: Multiplicity of the levels of specificity explains origin of the genetic code. Naturwissenschaften 89, 542-51. Review.
  52. Seligmann, H. 2002. Behavioural and morphological asymmetries in hindlimbs of Hoplodactylus duvaucelii (Lacertilia: Gekkonomorpha: Gekkota: Diplodactylinae). Laterality 7, 277-83. Invited paper.
  53. Seligmann, H. 2000. Evolution and ecology of developmental processes and of the resulting morphology: directional asymmetry in hindlimbs of Agamidae and Lacertidae (Reptilia: Lacertilia). Biological Journal of the Linnean Society 69, 461-81.
  54. Amzallag, G.N., Seligmann, H. 2000. Plant-to-plant interactions during physiological adaptation to salinity in Sorghum bicolor. Israel Journal of Plant Sciences 48, 247-54.
  55. Moraveç, J., El Din, S.B., Seligmann, H., Sivan, N., Werner, Y.L. 1999. Systematics and distribution of the Acanthodactylus pardalis group (Reptilia: Sauria: Lacertidae) in Egypt and Israel. Zoology in the Middle East 17, 21-50.
  56. Seligmann, H. 1999. Resource partition history and evolutionary specialization of subunits in complex systems. BioSystems 51, 31-9.
  57. Seligmann, H. 1998. Evidence that minor directional asymmetry is functional in lizard hindlimbs. Journal of Zoology, London 248, 205-8.
  58. Seligmann, H. 1998. Effect of environmental complexity on salt-adaptation in Sorghum bicolor. BioSystems 45, 213-20.
  59. Amzallag, G.N., Seligmann, H. 1998. Perturbation in leaves of salt-treated Sorghum: Elements for interpretation of the normal development as an adaptive response. Plant, Cell & Environment 21, 785-93.
  60. Amzallag, G.N., Seligmann, H., Lerner, H.R. 1997. Leaf malformation during early development in Sorghum. Evidence for an embryonic developmental window. Physiologia Plantarum 99, 470-6.
  61. Seligmann, H. 1997. Transmission of acquired adjustments to salinity in Sorghum bicolor. BioSystems 40, 257-61.
  62. Amzallag, G.N., Seligmann, H., Lerner, H.R. 1995. Induced variability during the process of adaptation in Sorghum bicolor. Journal of Experimental Botany46, 1017-24.
  63. Seligmann, H., Amzallag, G.N. 1995. Adaptive determinism during salt-adaptation in Sorghum bicolor. BioSystems 36, 71-7.
  64. Amzallag, G.N., Seligmann, H., Lerner, H.R.1993. A developmental window for salt-adaptation in Sorghum bicolor. Journal of Experimental Botany 44, 645-52.
  65. Seligmann, H., Amzallag, G.N., Lerner, H.R.1993. Perturbed leaf development in Sorghum bicolor exposed to salinity: a marker of transitions towards adaptation. Australian Journal of Plant Physiology 20, 243-9.

Doctoral Dissertation:

Microevolution of proneness to tail loss in lizards, supervised by Yehudah L. Werner and Avigdor Beiles, April 2003, most of the dissertation was published in a number of refereed articles. The dissertation lead to articles in the Journal of Zoology, London, the Biological Journal of the Linnean Society and the Proceedings of the sixth International Conference of the Israeli Society for Ecology & Environmental Quality Sciences.

Proceedings:

  1. Krishnan, N.M., Seligmann, H., Raina, S.Z., Pollock, D.D. 2004. Phylogenetic analyses detect site-specific perturbations in asymmetric mutation gradients. Currents in Computational Molecular Biology 2004, 266-7.
  2. Seligmann, H., Beiles, A., Werner, Y.L. 1996b. Morphological correlates of proneness of lizards to tail-loss. Proceedings of the sixth International Conference of the Israeli Society for Ecology & Environmental Quality Sciences, supplement.
  3. Seligmann, H., Beiles, A., Werner, Y.L. 1996a. Tail loss frequencies of lizards and predator specialization. Proceedings of the sixth International Conference of the Israeli Society for Ecology & Environmental Quality Sciences6, 520-2.

Internet

Seligmann, H.-*-=+: Did the boycott backlash? Proceedings of the International Advisory Board for

Academic Freedom Conference, in press, http://www.biu.ac.il/rector/academic_freedom/session8.htm.

Seligmann, H.2005. Boycott Israeli Academics? The Numbers Don’t Lie: They’re Already Blacklisted. Discarded lies, accessed October 10, 2005, http://discardedlies.com/entries/2005/10/boycott_israeli_academics.php

Seligmann, H. 2003. Organizing publicly one of many decennial silent boycotts: how old is the iceberg? A call for some transparency in reviewing processes. British Medical Journal, Http://www.bmj.com/cgi/eletters/326/7391/713/c#33902

Abstracts:

– H. Seligmann, G.N. Amzallag. 1995. Adaptation to salinity in Sorghum bicolor: A learning-like process? Israel Journal of Plant Science 43, 195.

– M. Wolf, H. Seligmann. 1996. Habitat options and speciation on islands. Israel Journal of Zoology 42: 87-8.

H. Seligmann, A. Beiles, Y.L. Werner, 1996. Morphological correlates of proneness of lizards to tail-loss. Israel Journal of Zoology 42, 87.

– H. Seligmann, S. Paz, A. Salvador. 1997. Climatic correlates of morphological evolution in an insular lizard, Podarcispityusensis. Israel Journal of Zoology 43, 115-6.

– H. Seligmann. 1997. Modes of predation specialization revealed by tail loss in lizards. Israel Journal of Zoology 43, 115.

H. Seligmann, 1997. Phylogenetic and ecological aspects of directional asymmetry in Acanthodactylus (Sauria: Lacertidae). Fifth International Congress of Morphology, Journal of Morphology 232, 320.

– H. Seligmann, 1997. Natural selection counter-balances evolution of sexual dimorphism in a lizard. Proceedings of the third World Congress of Herpetology.

– H. Seligmann, 1997. Tail injury alters activity patterns in Podarcismuralis (Reptilia: Lacertidae). Israel Journal of Zoology44, 87.

H. Seligmann, 1998. Morphogenesis and integration of growth of body parts in Lacertidae. Third Asian International Meeting.

– H. Seligmann, 1998. Side differences in injury frequency between hindlimbs as part of the evolutionary design of lizard limbs. (In hebrew with english abstract). Ecology and Environment5: 54-5.

H. Seligmann, 1998. Morphogenesis and integration of growth of body parts in

Lacertidae. Israel Journal of Zoology45: 320-1.

  1. Seligmann, G.N. Amzallag, 2000. The role of genetic versus developmental regulations in morphogenesis. Congress on “Modularity in Development and Evolution”, Hanse Institut, Delmenhorst.
  2. Seligmann, D.D. Pollock, 2003. Function and evolution of secondary structure in human mitochondrial mRNAs. Midsouth Computational Biology and Bioinformatics Society, Abstract 26.
  3. Seligmann, D.D. Pollock, 2003. The ambush hypothesis: hidden stop codons prevent off-frame gene reading. Midsouth Computational Biology and Bioinformatics Society, Abstract 36.
  4. Faiman, E. Razzetti, H. Seligmann, Y. L. Werner, 2005. Sexual dimorphism in snakes, with emphasis on eye size. Israel Journal of Zoology, 51: 63.
  5. Seligmann, 2005. Three distinct foraging modes among lacertid lizard species: sit-and-wait, widely foraging, and an intermediate, perhaps mixed strategy. Israel Journal of Zoology, 51: 76.
  6. Seligmann, 2006. Microgradient in morphology of Hoplodactylus duvaucelii on North Brother Island (Cook’s Strait, New Zealand). Israel Journal of Ecology and Evolution 52: 80.

Y.L. Werner, J. Moravec, H. Seligmann. 2007. Tail autotomy and regeneration in Sphenodon (Reptilia : Rhynchocephalia): Morphological, functional and evolutionary aspects. Journal of Morphology 268:1148.

  1. Seligmann, 2008. Do island extinction rates apply to mainlands? Israel Journal of Ecology and Evolution 54:249
  2. Seligmann, 2011. Frameshifted chelonian mitochondrial genes code for additional proteins in presence of antisense antitermination tRNAs and the special case of Lepidochelys. Societas Europaea Herpetologica European Congress of Herpetology and Deutsche Gesellschaft fuer Herpetologie und Terrarienkunde Deutscher Herpetologentag, Luxemburg und Trier, 25-29 September 2011, talk, abstract pages 85-6.

 

Talks:

H Seligmann, 2002. A molecular mechanism for developmental instability? Given as a Natural History seminar at the University of Chicago, USA, 8 of January 2002; and at the University of Calgary, Canada, 8 of May 2002; at Idaho State University, Idaho, 6 of August 2002.

  1. Seligmann, Pollock D.D, 2003. Function and evolution of secondary structure in human mitochondrial mRNAs. First Midsouth Computational Biology & Bioinformatics Society Meeting.
  2. Seligmann, Pollock D.D, 2003. The ambush hypothesis: hidden stop codons prevent off frame gene reading. First MidsouthComputationalBiology&Bioinformatics Society Meeting.
  3. Seligmann. 2004. Y a-t-il un lien entre les instabilités moléculaires et développementales ? September 2004, INRA, Versailles, France.

N.M. Krishnan, H. Seligmann, B.J. Rao. 2005. Natural selection on cloverleaf forming capacity fine-tunes the population frequency of human mitochondrial tRNA variants. Conference on tRNA Biology, Bangalore, India.

  1. Seligmann. 2007. Mitochondrial tRNAs as replication origins. Department of Microbiology, HadassaEinKaremHospital, The Hebrew University of Jerusalem, Israel.
  2. Seligmann. 2007. Life history implications of molecular mechanisms for developmental instability. Department of Biology, University of Haifa at Oranim, Israel.
  3. Seligmann. 2007. Molecular Mechanisms for Developmental Instability. Linnean Center for BioInformatics, Uppsala, Sweden.
  4. Seligmann. 2007. From molecular to developmental instability. Department of Life Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel.
  5. Seligmann. 2008. How many functions for tRNAs in human mitochondria. CEES lunch club, 6th October.

H.Seligmann. 2009. Research plans integrating collections and molecular data. SenckenbergNaturhistorischeSammlungen Dresden, Germany.